INNOVATION FOR PATIENTS

Advancing drug discovery & development through embedded collaborations and integrated service partnerships.

ABOUT US

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Sphaera is a drug discovery and development biotech, led by a team with 80+ years of combined life sciences experience. Having created value for its partners, collaborators and patients by advancing multiple preclinical projects into the clinic, Sphaera is committed to provide innovative therapeutics to those who need it the most.

  • Sphaera through its collaborations like Aayam, has access to global technologies and capabilities across the drug discovery & development spectrum
  • Scalable preclinical R&D capabilities under a single roof, with service experience and potential for new collaborations

COLLABORATIVE DRUG DISCOVERY

Sphaera is committed to bringing innovative therapies to patients, leveraging our expertise and experience through:

GLOBAL PARTNERSHIP AND ALLIANCES

  • Working with global partners to discover and advance preclinical R&D assets for improved patient outcomes.
  • Embedded relationships with different collaborative models, tailored for each project and partner.

PLATFORM TECHNOLOGIES ACROSS DIVERSE THERAPEUTIC AREAS

  • Proprietary platform technologies to accelerate, enable and repurpose drugs and novel therapeutics.
  • Therapeutic area expertise spanning oncology, metabolic disorders, CNS, mitochondrial dysfunction and rare genetic disorders.

FOCUS ON RARE AND NEGLECTED DISEASES

  • Integrated infrastructure, with therapeutic agnostic experience and the agility of a small biotech makes Sphaera ideally suited to tackle rare and neglected diseases.
  • Using repurposing to create a viable strategy for addressing rare diseases.

INTEGRATED DRUG DISCOVERY SERVICES

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CHEMISTRY

  • NCE design and synthesis, Hit-to-lead and lead optimization.
  • Library design and synthesis - various scaffolds like heterocycles, steroids, PROTAC, etc supported by complete Analytical capabilities.
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IN-VITRO PHARMACOLOGY

  • Assay development for enzymatic and cell- based screening.
  • Biomarker validation & profiling
  • IN-VITRO ADME Profiling studies
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IN-VIVO PHARMACOLOGY

  • Range of in VIVO pre-clinical efficacy, pharmacology, and safety models across diverse therapeutic applications
  • Development of complex, disease specific IN-VIVO models
  • Pharmacokinetic Studies in rodents

TEAM

NEWS & EVENTS